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TNPSC Medical Physics Exam Syllabus : Tamil Nadu Public Service Commission

Organisation : Tamil Nadu Public Service Commission (TNPSC)
Exam Name : TNPSC Medical Physics Examination
Standard : PG Standard
Subject Code : 263
Announcement : TNPSC Medical Physics Exam Syllabus
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TNPSC Medical Physics Syllabus

TNPSC Medical Physics Exam Syllabus are given below,

Related / Similar Syllabus : TNPSC Mining Engineering Exam Syllabus

UNIT I – Basics Of Radiological Physics:
Atomic Structure – Nuclear Transformation – Radioactivity and radioactive decay successive disintegration and equilibrium conditions – Interaction of Radiation with matter; electromagnetic radiation, charged particles and neutrons – Radiation attenuation coefficients – Radiation dosimetric concepts, quantities and units – cavity theories – Principles of Radiation detection and measurements – Radiation dosimeters and Radiation monitors.

UNIT II – Radiation Therapy Physics:
Radiotherapy with sealed and unsealed radionuclide – Mechanism of Telecobalt and linear accelerators (LINAC) – Physics of Modern radiotherapy machines – 3D CRT, IMRT, SRS & SRT, IGRT, cyber kinfe and Proton Beam therapy – Radiation Dosimetry protocol (TRS 398), Calibration of teletherapy equipments – Quality Assurance of Radiotherapy machines – Treatment Planning System (TPS) in radiation therapy & Quality assurance of TPS.

UNIT III – Physics Of Brachytherapy:
Introduction to Brachytherapy radionuclide and their properties – Production and construction of sealed – LDR, MDR and HDR Brachytherapy sources, their specification & calibration – reference Exposure rate – reference air kerma rate and air kerma strength – source calibration using an In-air set-up and calibration using a well type ionization chamber – source calibration using solid phantoms- source dosimetry – Interstitial, Intracavitary, intraluminal and pulsed brachytherapy – Monte Carlo Based source dosimetry – Quality assurance of brachytherapy equipments.

UNIT IV – Biological Effects Of Radiation:
Physics of radiation absorption – Cancer biology – Cell survival curves – Fractionation in Radiation therapy- dose rate effect – Oxygen Enhancement Ratio (OER) – Relative Biological Effectiveness (RBE) – Linear Energy Transfer (LET) – Molecular mechanism of DNA & chromosomal damage and repair – 4 R’s of Radiobiology – Bioeffect models; Time Dose Fractionation (TDF) and Extrapolated Response Dose (ERD) – Hyperthermia – Radioprotectors – Effects of radiation on embryo and fetus – Acute radiation syndrome.

UNIT V – Radiation Hazard Evaluation And Control:
Basic concepts of Radiation protection standards – philosophy behind radiation protection – External radiation protection – ICRP recommendations – Radiation dose limits – system of radiological protection – Equivalent dose, effective dose, committed dose – radiation exposures – Evaluation of external and internal radiation hazards and control – ALI-DAC- MPBB – planning and shielding calculations – radioactive waste disposal – Radiation emergencies, medical management and legislation.

UNIT VI – Diagnostic Radiation Physics:
Basic Physics of diagnostic radiology – Production of X-rays – diagnostic X-ray tube & its electrical circuits- X-ray tube rating – X-ray film, properties & Processing – Intensifying screens – Factors affecting radiographic imaging – fluoroscopy – Tomography – Various diagnostic X-ray tubes and shields – Computer Tomography (CT) and its generations – Quality assurance of diagnostic equipments – Digital substraction angiography (DSA).

UNIT VII – Physics Of Nuclear Medicine:
Scintillation counters – Different types of collimators – Gamma camera – single head and dual head scanners – Emission tomography – Single photon emission computed tomography (SPECT) – Positron emission tomography (PET) – Production of radioisotopes for nuclear medicine procedure – Technetium generator – Radiopharmaceuticals and their clinical applications.

UNIT VIII – Physics Of Ultrasound & Imaging:
Production & properties of ultrasound – propagation of ultrasound through body tissue – Acoustic impedance and acoustical characteristics in human body – ultrasound dosimetry – piezoelectric transducers – ultrasound scanning modes – Ultrasound cardiography (UCG) – Doppler effect – Double doppler shift – doppler systems – ultrasonic tomography – applications of ultrasound in medicine.

UNIT IX – Lasers In Medicine And Thermography:
Theory and production of medical lasers – Laser Tissue interaction mechanism – Applications of lasers in Dermatology, Oncology, Opthalmology – Application of ultrafast pulsed lasers in Medicine – laser blood flow meter. Hazards of lasers and their safety measures – Various types of electromagnetic radiations; UV, Visible, IR, their sources and detectors – Optical properties of tissues – Medical Applications of IR radiations in diagnosis and therapy.

UNIT X – MRI & Bio Medical Instrumentation :
Basic principles of Magnetic resonance imaging (MRI) – Larmor frequency – Resonance – Slice selection – localization within slices – Machanism of relaxation (T1 and T2) – contrast agents – MRI system – Electrocardiography (ECG) – Electroencephalography (EEG) – Electromyography (EMG) – physiological assist devices – pacemaker – defibrillators – heart lung machine – diathermy units – Dialysis units; Hemo & peritonial dialysis – Blood cell counter.

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